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Based on a sample of 20 children, an incidence of fever >38.0 °C of ≥35.0% was identified in the protocol as a holding rule for the study.
The stopping rule for the study on the basis of efficacy will be a nominal significance level of p = 0.003 (3 standard deviations) to maintain an overall Type I error probability of 5%.
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One classic example for a generative methodology is the set of Newton's rules for the study of natural philosophy.
With the exception of these first three (see section 4.4), Hume's rules of reasoning have a strong resemblance to Newton's four "Rules for the Study of Natural Philosophy" outlined at the start of Book 3 of the Principia (third edition).
There is no planned interim analysis and no "stopping rules" for the study as a whole.
Stopping rules for the study are if the local recurrence rate is higher than 3/4/6% after 2.5/5/7.5 years.
The stopping rule for this study will be used as a guideline rather than as a hard-and-fast rule.
The lack of maths rules him out for the study of physics.
In addition to accounting for the Bain-type deformation through the Cauchy Born rule, the study explicitly accounts for the shuffle displacements experienced by the internal ions in NiTi.
The same type of analysis (application of 'present calls'; rule set training) was performed for the study groups 'Berlin' and 'Leipzig'.
Bousoño's Teoría de la expresión poética (1952, rev. ed. 1966; "Theory of Poetic Expression") analyzed poetic devices and sought general rules and a scientific basis for the study of poetry.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com