Figure 3 illustrates the percentage reduction in R y and R a over time.
Any changes in R over time result from the assimilation of each new data point, leading to an updated estimate of R.
The change in the number of transcripts (R
(B ) Single imaging plane containing a group of PNs with significant changes in R over time (colored ROIs).
(H ) Plot of half-spindle ratio R over time in 11 single eGFP-centrin1/CENPA cells in which a single centriole was ablated.
(G ) Plot of half-spindle ratio R over time in 15 individual eGFP-centrin1/CENPA 2:1 cells that entered anaphase during live-cell imaging (black lines).
As a negative control we also plot the median R over time for control-ablated cells (laser pulse in the cytoplasm).
By plotting R over time in 15 cells that spend at least 7 min in metaphase before entering anaphase, we could directly observe how cells centered the plate position over time, while reducing the variability in metaphase plate position.
Building on a previously published model [ 33], we modelled the frequency of DDT-R over time in D. melanogaster using selection estimates from published fitness determinants documented in the Canton-S background in the absence of DDT.
In some cases, the more rigid 'epidemiological' structure imposed by EPP Classic may be preferable to allowing those models that vary r over time to follow too closely data with its own problems.
