Sentence examples for rs cells from inspiring English sources

Despite the well-described disease-promoting functions of RS cells, their development has remained obscure.

RS cells are derived from B lymphocytes of germinal center origin and arise due to a disturbance in cytokinesis by mononuclear Hodkgin cells., Two major signaling pathways are strongly implicated in helping RS cells evade apoptosis.

The presented study unraveled a novel route for the generation of multinucleated RS cells from mononucleated Hodgkin cells.

In Hodgkin lymphoma (HL), these cells are pathognomonic for the disease and named Reed-Sternberg (RS) cells.

IMR90 cells which arrested their growth after 8 10 weeks of culture were used as RS cells.

We addressed this open question by continuous live cell imaging to observe the generation of RS cells.

In contrast, CRI-G1-RS cells were significantly more susceptible to oxidative stress generated by HX/XO treatment (Fig 3B).

However, we observed no change in levels of total Akt or phosphorylated (active) Akt between CRI-G1-RR and CRI-G1-RS cells (Supplemental Fig. S10).

Expression of β cell-specific genes, such as insulin 1, insulin 2 and glucokinase [42], was also much higher in CRI-G1-RS cells.

Interestingly, CRI-G1-RS cells were more susceptible to both antimycin- (Figs. 2C and D) and oligomycin-induced cell death (Figs. 2E and 2F), but less susceptible to staurosporine-induced apoptosis (Figs. 2G and H).

Consistent with the cell viability data, the increase in caspase 3/7 activity was greater in CRI-G1-RR than in CRI-G1-RS cells at these mid-range doses (100 and 300 nM; Fig. 2H).