Sentence examples for rp grade from inspiring English sources

In figure 3, these relative values for IL-6 and TGF-β1 are plotted separately on a base 10 logarithmic scale for the patients without RP (grade 0), as well as for patients with moderate (grade I/II) and severe lung toxicity (grade III/IV).

Patients with AA genotype of AKT2: rs33933140 and MLD ≥ 15 Gy or V20 ≥ 24% had the highest risk of RP grade ≥ 3 compared with other groups (P <  0.0001 and P <  0.0001, respectively, Fig.  3A, B).

In our cohort, patients with age ≥ 58, MLD ≥ 15 Gy, and V20 ≥ 24%, and without receiving IMRT had a greater risk of developing RP grade ≥ 3, which verified the associations between the patient‐ and radiation dosimetric‐related factors and the occurrence of severe RP.

We also discovered that the association between rs33933140 and RP grade ≥ 3 was independent of MLD and V20, and further identified a group of patients with the highest risk of severe RP (patients with AA genotype of rs33933140 and MLD ≥ 15 Gy or V20 ≥ 24%).

Within 12 months of radiotherapy, 37 patients (14.2%) suffered RP ≥ grade 3. The associations between patient‐, tumor‐, and therapy‐related characteristics and RP ≥ grade 3 are listed in Tables  1.

Patients who did not experience RP ≥ grade 3 within 12 months of RT were censored.

The occurrences of RP ≥ grade 3 were 14.2%, which were similar to those reported previously 14.

The end point for this study was the development of RP ≥ grade 3. The time to the end point was calculated from the start of radiotherapy.

Among them, PI3CA: rs9838117, AKT2: rs33933140, and AKT2: rs11880261 were found to be significantly associated with the occurrence of RP ≥ grade 3 (Table S3).

Figure  2 is a plot of the RP‐free survival percentage for RP ≥ grade 3 for each genotype of PI3CA: rs9838117, AKT2: rs33933140, and AKT2: rs11880261 determined by the Kaplan Meier method.

Among them, three SNPs, PI3CA: rs9838117, AKT2: rs33933140, and AKT2: rs11880261, were found to be significantly associated with the occurrence of RP ≥ grade 3. Patients with the TT genotype of PI3CA: rs9838117, the AA genotype of AKT2: rs33933140, and the CT+TT genotype of AKT2: rs11880261 had a significantly increased risk of RP after radiotherapy for lung cancer.