Through the 1990s and into the current millennium, rapid advances in genomics and related disciplines have made it possible to envision a healthcare system in which patient care is routinely optimized through the use of information on individuals' genomes and their downstream products (i.e., transcriptomes, proteomes, and metabolomes).
It is shown that sophisticated fluid dynamic models of the growth process can nowadays be routinely used to optimize the growth conditions as a function of the reactor operative parameters.
We therefore call upon the various healthcare stakeholders in the U.S. and elsewhere to work expeditiously towards a national CDS infrastructure for genomic and personalized medicine, as the establishment of this infrastructure will be critical for enabling a future in which each patient's unique genetic profile is routinely considered to optimize health and healthcare.
In the presented case study, a Quality-by-Design approach was applied in order to optimize a routinely used method.
Similar methods based on differential scanning fluorimetry (DSF) are routinely employed in X-ray crystallography to optimize the quality and quantity of protein samples for further crystal screening30, but so far have rarely been employed in combination with cryo-electron microscopy (cryo-EM) studies.
To optimize migraine care, physicians should routinely educate their patients about early migraine symptoms, particularly for patients recently diagnosed with migraine, in addition to prescribing appropriate medications.
Prokaryotic cells must routinely respond to changing environmental conditions in order to optimize their growth or to simply survive.
To optimize a lead compound, research labs need to routinely and rapidly solve dozens of structures of a protein bound to different ligands, to find which offers the most favourable interactions.
Subsequently, sublingual nitroglycerin has been routinely used to dilate coronary arteries in CCTA examinations to optimize visualization of the coronary artery lumen and thus improve stenosis assessment [ 3, 15, 16].
To optimize coronary image quality, beta-blockers and nitroglycerin should be routinely administered in patients without contraindications for these drugs.
The discipline of nanomedicine defined as medical application of nanotechnology and related research has arisen to design, test, and optimize these applications so that they can eventually be used routinely by physicians (Freitas 1999).
