A specially developed sum of ranking differences routine (implemented in a Microsoft EXCEL VBA macro) was used for the evaluation of the dataset (1000*99 samples).
An automatic routine implemented as a Java application was created to determine the values of coefficients of the higher order terms of the WE that describe crack-tip fields.
This means, for example, that a library routine implemented in MATLAB can be invoked as often as necessary on the worker nodes of a cluster, started by a program implemented in C#.
The process is briefly summarized as follows: (1) The T1-weighted images were segmented into GM, white matter (WM) and non-brain voxels (cerebrospinal fluid, skull) using the 'new-segment' routine implemented in SPM8 [24].
This was accomplished by using a simplex optimization routine implemented in C [32], which searched for the set of P that minimized the negative log-likelihood value.
FST values were calculated using a routine implemented in the PopGen module of BioPerl [33] and stored in a 28×28 matrix.
There are a number of algorithms that can perform an inverse multidimensional Fourier transform such as the fft routine implemented in the R statistical package, the fourn algorithm of [26], or the FFTW numerical library of [27].
The parameter estimation routine implemented in gPROMS is based on maximum likelihood (SRQP iterative algorithm).
Sequences were trimmed and aligned using the MAFFT [ 58] routine implemented in Geneious 5.0 (Biomatters).
A comparison of haplotype frequencies between cases and controls was carried out using the haplo.score routine implemented in S-plus [ 27].
