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Routine coagulation laboratory measurements and analysis of coagulation factor activity were performed using the BCS® Analyzer and corresponding reagents (Siemens Health Care Diagnostics, Düdingen, Switzerland).
Laboratory analysis including routine coagulation parameters was conducted on on a daily basis during the ICU stay.
It was evaluated in a coagulation laboratory of a university hospital with respect to its technical characteristics in the determination of routine coagulation (prothrombin time, activated partial thromboplastin time, fibrinogen and single coagulation factors), chromogenic (antithrombin, and anti-FXa activity) and immunologic assays (von Willebrand factor).
Routine coagulation markers were measured.
The relationship between routine coagulation parameters and platelet count has not been explored.
There is no correlation between routine coagulation values and platelets at admission.
Other factors involved in coagulation testing include analyzing the cellular biology of coagulation, analysis of therapeutic interventions and integration of coagulation laboratories with patient care.
Routine coagulation tests evidence a prolongation of both prothrombin time (PT) and activated partial thromboplastin time (aPTT).
NOACs affect all routine coagulation assays [ 72].
Routine coagulation tests do not help to diagnose these DVTs.
The most important coagulation defects that may remain undetected with routine coagulation tests are platelet dysfunction and hyper-fibrinolysis.
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