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Clinical data collected for each patient included lactate dehydrogenase (LDH) and β2-microglobulin (β2-MG) levels, immunoglobulin (IG), blood biochemical functions, liver function, blood routine, coagulation functions, tumor markers, ferritin, bone marrow smear, and chemotherapy regimens.
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Coagulation functions were measured by rotation thrombelastometry (ROTEM®).
Patients' cardiopulmonary and coagulation functions were assessed before operation and no apparent surgical contraindications were identified.
Thus, hypothermia and haemorrhage seem to have different effects on the coagulation function.
Altered coagulation function after trauma can contribute to development of venous thromboembolism (VTE).
Severe trauma impairs coagulation function, but the trajectory for recovery is not known.
All the individuals were Han Chinese and the healthy individuals were clinically evaluated to address normal coagulation function and routine blood tests.
Patients with cirrhosis exhibit impaired coagulation function.
Different resuscitation pressures had no effect on coagulation function.
Physical examination and routine laboratory studies were performed at baseline and every week on-treatment, including complete blood cell count, electrolytes, liver and renal function tests, urine examination and coagulation function; tumor markers every cycle; electrocardiogram every two weeks and echocardiogram at baseline, and every 3 cycles.
The primary parameters were the overall mortality, renal function, bleeding and coagulation function.
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