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Many of the synthetic routes for development of nanomaterials use toxic reagents that make them unsuitable for biological use and also have adverse effect on the environment.
The discovery of over 50 novel DNA methylation-based biomarkers of breast cancer may provide new routes for development of DNA methylation-based diagnostics and prognostics, as well as reveal epigenetically regulated mechanism involved in breast tumorigenesis.
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Single-walled carbon nanotubes (SWCNTs) were incorporated at low loading (up to ∼1 wt%) into an unfilled aerospace-grade epoxy system, to impart electrical conductivity while maintaining structural bonding capability, as a route for development of a structural and conductive adhesive.
We note that from the results in our earlier work [20], the addition of a top gate tends to decrease E a, but as the top-gated geometry provides very good heat sinking, and top gates will ultimately be needed for optimized device design, we see this as the best route for development of a graphene nanoribbon device that retains its gapped behavior at high bias.
Our inverse bifurcation method exploits inherent structural properties of bistable switches in order to estimate kinetic parameters of bistable biochemical networks, opening a promising route for developments in Chemical Reaction Network Theory towards kinetic model identification.
These observations serve as a basis to indicate novel routes for the development and design of effective anti-Leishmania drugs.
The aim of this work is to explore potential routes for the development of ecology-based alternatives for animal production.
The nanopatterned devices are demonstrated to be dissolvable in water within less than 2 min, opening interesting routes for the development of physically transient organic photonic platforms.
Decreased global demand for health workers and indications that South African SHWs primarily use migratory routes for professional development suggest that health worker shortages as a result of permanent migration no longer pertains to South Africa.
Until recently, association genetic studies for adaptive variation have been limited in conifers (but see [ 62, 65]) due to the high cost and time required by traditional routes for the development of marker resources.
Besides these two major molecular types of CRC, two other well-defined alternative routes for CRC development have been described as follows: homozygous germline inactivation of the base excision repair gene mutY homologue (MUTYH) leading to a polyposis phenotype and the concomitant methylation of many gene loci resulting in the CpG island methylator phenotype (CIMP) [ 6].
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