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The central route would require building a canal and aqueduct some 1,240km (770 miles) long to the Beijing area.
The alternative route would require many more miles and days on the mountain, and might add new hazards as well, including a crossing of the McKinley River.
Hanna pointed out many advantages of the Panama route: it was shorter than the Nicaraguan route, would require much less digging, and had existing harbors at either end.
Synthesis of less functionalized carborhodamines using this route would require robust, multistep protection deprotection strategies; such considerations have stymied the preparation of fluorophores such as compound 5 and related fluorogenic N-acyl derivatives.
We cannot say whether the relevant factor was the added length of the journey or the fact that that route would require a greater initial starting angular deviation from the goal vector.
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Opening the routes would require about $33 million of investment in Russia and about $4.2 million in Canada, for air traffic control computers, communications lines within Russia and between that country and the United States, and training of air traffic controllers.
The five routes would require NOK 725,000 in annual subsidies.
With river transportation denied, the alternative land routes would require months of travel instead of days.
Devoting such a large number of troops to pillaging oilfields and protecting oil pipelines and transportation routes would require a more permanent presence in Iraq and far more troops than the United States has available.
Ukrainian energy adviser Bohdan Sokolovsky says Russia has shipped natural gas along a route that would require Ukraine to cut domestic consumers out before it can deliver gas to the Balkans.
The transmigration could either take place via the paracellular route which would require a transient BBB breakdown, or via the transcellular pathway through the endothelial cell body.
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