Table 3 summarizes patient's gender, age, medical condition, the route of injection, injected total number of cells, and patient's satisfaction assessment.
The inconsistent results in preclinical models may be due to several variables such as source of MSCs (murine syngeneic or allogeneic, or human), tissue of origin of MSCs, timing of treatment, number of cells injected, route of injection and treatment regimes, different culture conditions, as well as differences in mouse strains and animal housing conditions.
The amount of BTX-A injected, the route of injection, the number of injections, and the injection site varied among studies.
However, intra-femoral injection of a subset of murine marrow stromal cells has shown limited engraftment at the site of injection 4 6 weeks post-transplantation, suggesting that the quality of the cells injected as well as the route of injection are major determinants of engraftment [ 37, 38].
These results show that cells injected post-MI display comparable tissue distribution profile regardless of the route of injection and that there is no time effect for cardiac cell accumulation for injections performed 1 to 3 days post-MI.
Both conditions surrounding psychostimulant administration and the route of injection can affect the behavioral response to these drugs (Browman et al, 1998), and can vary the magnitude of neuronal activity (Porrino, 1993).
However,i/p route of injection did not showed significant changes (Tables 7 and 8).
Furthermore, we analyzed and compared the route of injections with their different benefit index.
Results of pathogenicity experiments indicated that death can occur from the i.c. and i.m. routes of injection, although gt2 viruses showed lower lethality to mice when injected i.m.
We injected zoledronate either i.v. or i.p. and compared these routes of injection (Fig. 1B).
To study the effects of ketamine and two doses of medetomidine administered by two routes of injection in a genetically diverse population of rabbits.
