In the case of determining routes and locations for constructing distribution centers on hazardous materials (Hazmat) transportation, risk and cost are considered as the main attributes for developing mathematical models.
So a slight adjustment was called for last week, when the Ford Motor Company staged a race, of sorts, on the major arteries leading into Manhattan, for the purpose of determining which route was most congested during the morning commute.
In the present study, we show that the route of administration determines the efficacy of CpG to stimulate immune responses after in situ tumor destruction.
Since NYVAC also infects non-hematopoietic cells and the route of administration determines the cell types that are infected, cross-presentation probably plays a major role in the induction of vaccinia virus-induced CD8 T-cell responses [47], [48].
CIA, EAE, and EAU in general are induced by s.c. immunization, suggesting that the route of immunization determines the Th17 pathology of these autoimmune models.
It is already known from BDV infection of rats that the route of infection determines the severity of disease and that an early up-regulation of BDV-specific CD4 T cells can efficiently protect against infection by the virus (37 ).
In this paper we address a problem consisting of determining the routes and the hubs to be used in order to send, at minimum cost, a set of commodities from sources to destinations in a given capacitated network.
The Mössbauer technique is sensitive to all the FeS clusters present, regardless of their oxidation states, and thus offers a direct route to determine the proportion of oxidized and reduced clusters.
One route to determine the fine details of the processes that control the operation of solid CP-based devises isolatinging the polymer chains.
Other routes of administration determine the degree of severity of such clinical symptoms, with oral administration exhibiting minimal effects.
