What makes the play moving is that, instead of taking the familiar escape-route of death, the characters face up to eternal separation and the hell of a loveless existence.
Therefore, in the presence of zVAD-fmk, the residual protease caspase-10 activity likely promotes an alternative route of cell death, leading to apoptosis-like cell death.
Initiator caspases can trigger an alternative route of cell death involving mitochondria.
Further experiments are required to determine the exact route of cell death and mechanism of action.
The observed shift in SSC that resulted from our drug treatment would indicate an increase in cellular granularity, consistent with apoptosis being the route of cell death induced by EXEG 1706.
Induction of PCD through the activation of caspases (apoptosis) is the best characterized route to death in most cell types [ 1].
This makes the rate of death en route to Italy so far this year 4.13 per 100 people.
Nick's journal, like the historical record, becomes a roster of death, lengthening even en route home.
When the state sign route system was created in 1934, Sign Route 190 was assigned to the portion of Route 127 west of Death Valley Junction, while the remainder to Baker became part of Sign Route 127.
If it tips over as it careens down the road, swerving in mad competition with equally crowded rivals as they seek to pick up the next group of prospective passengers on this route, your likelihood of death or, at least, dismemberment will be extremely high.
At the age of 15 he was highly praised by the Tennyson scholar Christopher Ricks and the Milton scholar John Carey, who called the book "a jubilant, lawless debut" in which Nolan had "plummeted into language like an avalanche, as if it were his one escape route from death - which, of course, it was".
