HPV testing has considerably better sensitivity than cytology providing the same extent of safety with fewer rounds of screening.
Using R-3-chloromandelic acid as a model substrate, a total of 53 mutants were constructed based on rational design in the two rounds of screening.
The original signature-tagged mutagenesis (STM) technique has certain technical limitations, including high variation in signal intensities after hybridization, owing to the variability of the tag sequences, necessitating further rounds of screening.
Similarly, our initial knottin RGD-loop libraries contained very few integrin binders, which were enriched over multiple rounds of screening.
After the beads were washed 5 times with PBST, the phages recovered from the HVGGSSV peptide-coated beads were amplified in E.coli BLT5615 (Novagen) for the subsequent rounds of screening.
Transformants were subjected to three rounds of screening.
These are cumulative data from three rounds of screening.
Tracking the clients with non-malignant findings during their subsequent rounds of screening showed that 781 of the 920 (84.9%) eligible women returned for subsequent rounds of screening.
Firstly, since all trials examined multiple rounds of screening, we focused on the time lag to benefit for multiple rounds of screening.
For a three-state model, suppose we only have data on two rounds of screening.
Extrapolation required an assumption of constant benefits and harms from additional rounds of screening.
