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A biomechanical study by Zionts et al. [7] demonstrated that crossed pinning is more stable than lateral pinning in rotational testing as well as varus and valgus loading.
Although higher-end materials testing machines will enable torsional and/or rotational testing, simpler, less expensive systems rarely offer these capabilities.
Dopaminergic functional activity in the striatum was assessed by [18F]FDOPA-PET, measurement of striatal dopamine (DA) and DA metabolite levels, tyrosine hydroxylase (TH) immunostaining, and methamphetamine-induced rotational testing.
Following the rotational testing, the animals were put back into their cages.
Therefore, these measurements can actually be considered as the gold standard for rotational testing.
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The results were counted as the total amount of net ipsilateral rotations per 120 min. One day after the drug-induced rotational test, rats were anesthetized with an overdose of pentobarbital (90 mg/kg, i.p., Mebunat, Orion Oyj, Espoo, Finland).
Rotational test to failure was performed with a material testing machine.
An apomorphine‐induced rotational test revealed no Parkinsonism‐like behavior in the NH treated groups.
The test rotor exceeded 350 Hz (21,000 rpm) in the rotational test, and whirl vibration was absent.
In the rotational tests, the rotor speed exceeded 380 Hz (22,800 rpm), and whirl vibration did not occur.
The rotational test with respect to the VSCC can be used as a tool for assessing vertical canal function.
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