Primary stability of the two geometries was evaluated using two modes of failure: direct distraction (pull-out tests) and sagittal/coronal rotation (lever-out tests).
The knee joint was aligned with the center of rotation of the lever arm, and the lever arm was attached just above the ankle joint.
The effect of additions of MgADP to rigor cross-bridges could result from rotation of the lever arm of smooth muscle myosin, but this need not imply that ADP-release is a significant force-producing step of the physiological cross-bridge cycle.
If the working stroke involved an inherent clockwise rotation of the lever arm about the thick filament when looking Z-wards, the S1 S2 junction would move clockwise about the thick filament (Fig. 10F) and the cross-bridge would be straightened.
The apo structures of myosins V, VI, and II, which are believed to mimic the actin-bound state for myosin, show that this transition is accompanied by closure of the 50 kD cleft and rotation of the lever arm to yield a power stroke.
Site directed mutagenesis in the SH2/SH1 hinge--converter interface, and in the converter domain proper, provided clues for how it performs the conversion of linear translation in the Switch 2 helix to the rotation of the lever-arm [ 60].
Three generalized coordinates are defined in Figure 5(b), namely, the displacement of the PEA (xPEA), the rotation angle of the lever (θlever), and the linear displacement of the central platform (xeq).
The working stroke is produced by lever arm rotation about a pivot point near the ATP binding site [7], [8].
The rotation axis of the lever arm and wrist joint were adjusted and positioned according to the Kin Com System Manual.
The center of rotation of the dynamometer lever arm was aligned with the hip joint center of rotation through the greater trochanter of the test limb.
Notice the rotation movements when doing lever bar movements.
