Sentence examples for rotation hypothesis from inspiring English sources

Therefore, the minimal rotation hypothesis is valid in 21.7% of residues critical for binding (whereas ours is in 31.8%) corresponding to 18% of binding-sites.

On the basis of the docking results obtained using a dataset of 63 complexes representing 20 different proteins, the authors proposed the minimal rotation hypothesis.

In our dataset, the minimal rotation hypothesis applies to ~22% of (37/170) of all sterically critical residues, while the other 78% are accommodated by larger rotations that may or may not lead to a rotamer change, almost four times the cases covered by the minimal rotation hypothesis.

Therefore, while the minimal rotation hypothesis may be a useful approximation in docking simulations if validated in a larger dataset, it still remains to be seen if it is applicable to explain side-chain flexibility upon binding.

Furthermore, such widespread rotamer transitions represent changes between energetically separate states, thus placing doubt over the validity of the minimal rotation hypothesis outside the context of docking simulations and the small dataset upon which it was developed (Zavodszky and Kuhn, 2005).

Overall, only in 37 critical cases (2 flexible and 35 rigid side chains) a dihedral angle change of less than 15° is responsible for the change, in agreement with the minimal rotation hypothesis (Zavodszky and Kuhn, 2005) distributed among 34 binding-sites (out of 188).

The implemented large rotation theory has six kinematic parameters expressed by five nodal degrees of freedom (DOFs) based on first-order shear deformation (FOSD) hypothesis.

After a period of 12 months, the sector that had received only ergonomic guidelines will receive job rotation considering the hypothesis of this study in relation to its effectiveness.

This correlation supports the hypothesis that rotation can be genetically uncoupled from fate in that a gain/loss of the ability to choose the right direction of rotation is reflected in an increase in numbers in the D/V and A/P classes, respectively.

Furthermore, major medial releases led to the least external rotation, again confirming our hypothesis.

2) Another control should be included, which is the addition of phenamil, a specific inhibitor of the sodium-driven motor, to the wildtype cells-this will stop flagellar rotation, and if their hypothesis is correct, there will be less LPS in the supe, which will stimulate less apoptosis.