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With a more comprehensive understanding of the tissue-specific roles of distinct metabolic signaling pathways controlling energy homeostasis and the cross-talks between these pathways during aging may lead to the development of more effective therapeutic interventions not only for metabolic dysfunction but also for aging.
Through computational modeling and experimental evaluation, we explore the signaling roles of distinct NF-κB dynamics that occur in multiple timescales.
As such, the functional roles of distinct histone acetylations are largely unexplored.
Normal inner ear function depends on coordinated roles of distinct cell types.
A major challenge for the future is to understand the cellular roles of distinct caveolae-associated protein complexes.
– Individual and careful study of each GTPase is therefore warranted to uncover the unique roles of distinct GTPases.
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The present study further illustrates the essential role of distinct adsorption modes in photocatalytic events.
The present study is designed to investigate the effects of interleukin-4 (IL-4) on expression of interleukin-6 (IL-6), as well as to examine the role of distinct sources of reactive oxygen species (ROS) in this process.
Against this background, the objective of this paper is to substantiate the trend from transnational private to international state-driven governance by analyzing the role of distinct state bureaucracies in the emergence, diffusion, and reshaping of private natural resource governance systems.
Our data demonstrates IUE mediated cortical gene silencing as an excellent approach to study the role of distinct molecules for epilepsy associated focal brain lesions and suggests LRP12 and lipoprotein homeostasis as potential molecular target structures for the emergence of epilepsy-associated FCDs.
However, the role of distinct classes of long chain dietary fatty acids during TB infection has not been well investigated to date.
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