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In this context, we also investigate the roles of binding sites of known cofactors such as FOX and SP1 in silico.
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While only RS has been analyzed by previous researchers, the role of binding illustrated by M y can now be explored.
These flow-mediated transport mechanisms are also used to interpret the role of binding site densities and injury size on initiating coagulation and fibrin deposition.
To better define the role of binding affinity in forming a protein-ligand complex, a structural characterization for putative human off-targets was recently performed on Nelfinavir, a potent HIV-protease inhibitor with pleiotropic effects in cancer cells [2].
Barril and Morley carried out a detailed analysis on the role of binding pocket flexibility in ligand docking [28].
Common ER chaperones may prevent aggregation and misfolding of procollagen C-propeptide in their traditional role of binding unfolded polypeptide chains.
The results demonstrated that Glu11 exerted its role of binding site through forming H-bond by the interaction of its side chain with the Lys anchor in the frame of TP5 (Fig. 7A, C).
Even the unstructured N-terminus plays an important role of binding to the ribosome.
The role of binding of Ca2+ to F2 TnC seems to be, as in vertebrate muscle, twofold.
Furthermore, there are not studies regarding the role of binding partners of the disease-related proteins in the oligomerization process.
This method is based on the assumption that SPF represents correctly the role of binding sites in transcription regulation.
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