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This study highlights the crucial role translation initiation plays in yeast CFPS and offers a simple platform to study IRES sequences.
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Oakley and Davis have clashed with the team's young stars over offensive roles (translation: the old guys wanted more shots).
Ribosomal protein S1 (RpsA), the largest 30S protein in ribosome, plays a significant role in translation and trans-translation.
The 5'UTR of mRNA plays a critical role in translation regulation by influencing mRNA stability and translation efficiency.
To verify that the action of eEF1A1 is independent of its role in translation inhibition, we tested eEF1A1 knockdown conditions in combination with inhibitors of translation elongation.
In conclusion, our data underline the role of translation factors for cell proliferation and support the concept of translational oncogenes.
The final goal was not to demonstrate the specific role of translation.
Eukaryotic initiation factor 4G (eIF4G) plays a central role in translation initiation through its interactions with the cap-binding protein eIF4E.
The significance of electrostatics in the tunnel remains relatively uninvestigated, yet they are likely to play a role in translation and secondary folding of nascent peptides.
In contrast, uORF1 may have a positive role in translation of HIC mRNA.
The cytoplasmic localization of ZNF9 is consistent with its proposed role in translation.
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Justyna Jupowicz-Kozak
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