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In MM, MYC has a crucial role pathogenesis: expression of MYC is increased in newly diagnosed MM compared with monoclonal gammopathy of undetermined significance, suggesting that increased MYC expression is associated with progression from monoclonal gammopathy of undetermined significance to MM.
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Studies are on-going to evaluate this protein and its role in pathogenesis.
We are currently studying the basic microbiology of c-di-AMP and its role during pathogenesis.
In many neuropsychiatric diseases alterations in the levels of transmitter substances appear to play a major role in pathogenesis.
Muller, D. A. & Young, P. R. The flavivirus NS1 protein: molecular and structural biology, immunology, role in pathogenesis and application as a diagnostic biomarker.
Due to the importance of acetylation and potential role in pathogenesis, acetylated proteins and enzymatic machinery for acetylation have been used as drug targets.
ROS plays an important role in pathogenesis of diabetes, so natural antioxidants could help us in managing diabetes.
However, whether they play a role in pathogenesis of neurodegenerative diseases is unknown.
Altogether, these results suggest that Brn2 may have a role for pathogenesis of lichen planus.
Several mechanisms have been proposed to explain its role in pathogenesis of the gut.
So apparently their role in pathogenesis is doubtful for bad bugs.
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