Sentence examples for role of the modification from inspiring English sources
Motivated to test the role of the modification in terminating the primer-binding sequence and thus limiting run-on transcription, we asked how the modification of RNA could be accomplished.
Therefore, it would be very interesting to test if Rpb1 sumoylation and the role of the modification are conserved between yeast and mammalian cells.
One strategy to circumvent this problem is to identify and mutate specific O-GlcNAcylated residues in target proteins to probe the physiological role of the modification.
Because of the potential regulatory role of the modification, we conducted this analysis in synchronous cultures to determine whether SUMOylation levels of Tpz1 vary during the cell cycle.
Our result that turning on Pkh-kinases dissembles pre-existing eisosomes argues against the notion that this is the exclusive role of the modification, although it does not rule it out conclusively.
These material parameters are influencing the activation volume ΔV# which plays a role on the modification of the fragility index.
Integrating this knowledge within an extensible framework would provide a valuable means to organise the information and to explore the role of the modifications.
O-glycosylation of the Plasmodium sporozoite surface proteins CSP and TRAP was recently identified, but the role of this modification in the parasite life cycle and its relevance to vaccine design remain unclear.
These previously published reports have not, however, addressed the physiological role of this modification in vivo in the context of the immune system.
However, phenotypic characterization of these mice and embryo fibroblasts derived from them, has established the role of these modifications in the regulation of the size of several cell types, as well as pancreatic β-cell function and glucose homeostasis.
We speculate that the role of this modification may be for nuclear localization of the cysteine-generating pathway under conditions where nuclear glutathione demand is high.
