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Although, currently, growth disorders are still diagnosed and treated on empirical bases, it might soon be possible to stratify patients predominantly by genetic defect, with treatment based on our molecular understanding of the role of the affected gene in the disease.
In cancer, selection at the level of the cell type differs from selection at the level of the host organism because the role of the affected cell type in the multicellular organism is at odds with maximizing the number of its progeny cells.
The severity of these diseases can vary dramatically, depending on the nature of the mutation and the role of the affected protein.
The aim of the study was to identify the mutation causing the SA defect and reveal the role of the affected gene in spermatogenesis.
The phenotype of the SE mutant reveals a role of the affected protein in the early steps of organ elaboration and a role in the regulation of gene expression via chromatin modification was also suggested [ 17].
The glucose sensing role of the affected gene product implies an intriguing phenotype: the blood glucose threshold for insulin secretion is increased, but the functional capacity of beta cells is preserved; a rightward shift of the dose-response curve is observed [ 40].
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The annotated functional roles of the affected genes suggested that virulent Francisella infection suppressed cellular processes including mRNA processing, antiviral responses, intracellular trafficking, and regulation of the actin cytoskeleton.
Given the role of the top affected genes, we sought to examine the global trend.
For these reasons, decision specific anxiety measures are needed in order to evaluate the role of this affect on cognitive decision making processes.
This allows to suggest a negligible role of the interface affecting the hardness and modulus of TiAlSiN thin films.
To analyze whether the role of autophagy affecting the glycosylation in tongue squamous cell carcinoma is dependent on the variation of the hypoxia, we designed the OGT protein detected based on the autophagy knockdown while HIF-1 α was inhibited.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com