Sentence examples for role of scaffold from inspiring English sources
Experimental studies are often performed to investigate the role of scaffold architecture on vascularized tissue formation.
This work is focused on the in-silico determination of the role of scaffold microstructural anisotropy in bone tissue regeneration.
In an attempt to recapitulate exact in vivo microenvironment of osteogenesis, role of scaffold architecture and material chemistry in regulating cellular differentiation is elaborated.
This is the key point that explains the role of scaffold proteins.
The role of scaffold proteins in MAP kinase signalling is well studied in budding yeast and the importance of Ste5p adaptor protein for bringing together the MAPK components module is well established [ 54 56].
Our inability to demonstrate an obvious role for KSR in mediating BRAF binding to CRAF or CRAF activation by BRAF suggests that the mechanism underlying dimerization here may be different from those described in flies, but clearly additional studies are required to investigate further the role of scaffold proteins in mediating the phenomena we report.
While these scaffold strategies are conceptually attractive and supported by numerous basic science studies, further rigorous investigation including preclinical and randomized clinical trials are needed to critically evaluate and fully understand the role of scaffolds in tendon repair and regeneration.
In a study that exemplifies the role of scaffolds in driving PKC function, CKAR was fused to the anchoring protein AKAP79 [ 20].
In fact, there is an increasing awareness that the role of scaffolds is not only to deliver cells to enhance tissue regeneration, and the use of cell-free scaffolds has been proposed and is gaining popularity.
More recently however, new topics emerged, such as the role of scaffolds to structure student learning and students' self-reflection in PBL (Hmelo-Silver 2004; Hmelo-Silver et al. 2007; Simons and Klein 2007; Williams 2001).
These ideas were supported by a study of Levchenko et al. [ 57] who explored numerically the role of a scaffold protein in a MAPK pathway, and found that for any generic scaffold there exists a concentration value optimal for signal amplitude.
