Sentence examples for role of damage from inspiring English sources

This is beneficial to develop enhanced finite element models to investigate the role of damage accumulation on bone damage repair during remodelling.

This paradox is illustrated with a case report, highlighting the difficult diagnostic criteria, the potential role of Damage or Pathogen Associated Molecular Pattern Molecules [DAMPs and PAMPs] that drives aspects of ongoing inflammation within the transplanted organ as well as the intestine, and the therapeutic strategies applied.

Due to its relative simplicity, ease of genetic manipulation and short lifespan, the nematode worm Caenorhabditis elegans (C. elegans) is an attractive model to explore some of the open questions regarding the role of damage accumulation in ageing [16].

In addition to the role of damage, the contribution of changes in the levels of purposely used metabolites remains unclear.

In particular, these studies have sought to resolve the role of damage to the protein versus the HS chains, the potential role of bicarbonate and reaction pH in modulating these reactions, and whether such oxidant damage alters the biological activities of this important vascular macromolecule.

To further elucidate the potential role of damage to perlecan by peroxynitrite in vascular disease, the mechanisms and functional consequences of exposure of human arterial endothelial cell-derived perlecan (the major proteoglycan component of the arterial subendothelial matrix), to peroxynitrite have been examined in detail.

Delineating the relative roles of damage and architectural degradation on trabecular bone strength will provide insight into the most beneficial targets.

These findings may apply to other damage types, suggesting a causal role of cumulative damage, as opposed to individual damage types, in organismal aging.

Massimiliano Mellone (University of Southampton, UK) described the role of DNA damage and DNA damage response (DDR) pathways in myofibroblast transdifferentiation.

Furthermore, an analysis of the role of both damage and aging in cancer argues against "a decline, caused by accumulation of molecular damage" as a cause of aging.

These reports suggest a role of oxidative damage in adult cardiac progenitor cell behavior.