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Although these data point to a likely role of AID in disease pathogenesis in CLL, the evidence for in vivo AID activity is scarce: typical AID off-target damage, such as somatic mutations of the BCL6 gene [41] or c-myc/IgH translocations [42] are very rare events in CLL and IgVH genes in AID-expressing CLL cells are frequently unmutated.
The role of aid is changing.
What is the role of aid in this context?
DfID should revisit its decision and its understanding of the role of aid in middle-income countries.
It has certainly generated a much needed debate about the role of aid and the state of development in Africa.
This shift has led to calls for the role of aid and development co-operation to be reassessed.
Similar(34)
How many times will it require before Congress stops its co-dependent role of aiding and abetting the administration's addiction to saber rattling?
The dignitaries and canons constituted the chapter and had the primary role of aiding the bishop in the governance of the diocese.
The role of aids and appliances again indicates the importance of the workplace to allow individuals to self-manage their pain to optimise performance.
Further clarification of the roles of AID- and/or TDG-mediated demethylation in PGCs is still required.
Finally, this approach would be consistent with the current thinking on the evolving role of UK aid, especially in the case of emerging powers such as India, where the focus has shifted from aid to investment in technical assistance and cooperation as a means of boosting bilateral business and trade.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com