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A combination of the metabolomic approach and these bioresources has been demonstrated to be a smart strategy to uncover the role of a functionally unknown gene.
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Thus, our study establishes a new role of GD2 as a functionally active biomarker for anti-cancer therapy.
Indeed, because the role of the functionally uncharacterized Cln5 protein remains unclear these studies may offer clues to the unraveling of its possible function(s).
In addition, sequence alignment of Hs II, demonstrated that this region was evolutionarily conserved between human, mouse, cow, dog and oppossum, suggesting the possibility of a functionally important role for this DNA element (Figure S1).
These results clearly indicate a link between the different motifs within the core-promoter and transcriptional features of the gene and are in favour of a functionally independent role of the TATA-box, the TATAΔ- and the TC[-39,-26]-PLMs TC[-39,-26]-PLMs TC[-39,-26]-PLMs TC[-39,-26]-PLMs
The fact that a causative structure is called upon to express a Stimulus-subject relation suggests that the role of a Stimulus is taken to be functionally identical to a Causer.
Our data suggest a protective role of functionally active lymphocytes directed against MSI-H CRCs, which may prevent tumour cell dissemination and metastasis formation in distant organs.
Promotion of angiogenesis is a well-known component of wound response and the role of VEGFA, both functionally and genetically in AMD is well established.
However, the exact role of PDGF-A(L) and how it functionally differs from the shorter isoform is not well understood.
As myoepithelial cells had been reported to show degenerative changes, we decided to investigate the possible role of functionally deficient myoepithelial cells in the development of sialadenosis.
Our findings provide the first indication of the role of functionally active Cn in follicular keratinocytes.
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