Sentence examples for role is specific to from inspiring English sources

Interestingly, NRBP1 has also been shown to be involved in intestinal progenitor cell homeostasis with tumor suppressive function [ 66], suggesting its role is specific to the cellular context.

This role is specific to SerRS among all tRNA synthetases and is independent of its well-known aminoacylation function in protein synthesis.

The latter niche role is specific to JAK/STAT signaling in CySCs and cannot be fulfilled by Hh signaling, another CySC self-renewal pathway (Amoyel et al, 2013).

We for the first time show that this regulatory role is specific to zebrafish Mt2 and represents a novel, non-canonical function of MT2, most likely not attributed to metal-binding capabilities of MT proteins.

It is tempting to speculate that miR-218 may play some role that is specific to progression from inflammation to transformation in the colon, but this hypothesis remains to be evaluated.

In particular, the PV interneurons appear to provide a general amplification of inhibition, rather than having any role that is specific to SSA.

In particular, the PV interneurons appear to provide a general amplification of inhibition, rather than having any role that is specific to SSA. 7) The authors show using the expression of chanelrhodopsin in cre-PV and cre-SOM mice that both types of interneuron exhibit SSA.

Thus, the apoptotic role of ARTS/Sept4 is specific to certain cell lineages and involved in cancer development.

Finally, the Wnt-activating role of USP7 is specific to APC mutations; thus, it can be used as a tumor-specific therapeutic target for most CRCs.

In contrast, TNF-α-induced JNK activation was not affected, which again proves that the role of Hsp60 is specific to the IKK activation.

Thus, an observation that NHE1 acts upstream of ERK in the signaling pathway, which leads to the increased proliferation of A498 cells, suggests that this role of NHE1 is specific to A498 renal cancer cells.