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"You have an active role in fate.
Researchers have studied the expression of lncRNAs in purified mouse brain cells and found their role in fate determination of oligodendrocyte precursor cells (OPC) [120].
Aurora and Polo kinases also play a role in fate determination by inhibiting the excess self-renewal of neuroblast (Wang et al. 2007; Lee et al. 2006c; Wang et al. 2006).
As model system, we used the Drosophila bristle lineage where at each division N plays a crucial role in fate determination.
However, other commonly overrepresented terms include stem cell differentiation/development consistent with a role in fate transition from ground state pluripotency.
These and other findings have been interpreted as dorsal to ventral transformations and as evidence that sal has a role in fate specification for particular branches (Chen et al., 1998; Kuhnlein and Schuh, 1996).
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The homeodomain TFs have been shown to play key roles in fate-determination of ES cells by contributing to the core regulatory networks.
The microenvironment of myocardium plays an important role in the fate and function of cardiomyocytes (CMs).
It has become increasingly clear that chromatin regulators play an important role in cell fate determination.
Some families were never reunited, and some of the children, now adults, resent the organization's role in their fate.
Dey, B. K. et al. The histone demethylase KDM5b/JARID1b plays a role in cell fate decisions by blocking terminal differentiation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com