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I hope Grieve finds a new role consistent with his talents.
We suggest these oligomers play a role, consistent with past observations in prokaryotes and analogous to nucleosome association in eukaryotes, as binding sites for enzymes responsible for packaging of the bacterial nucleoid.
Paradoxically, Naip-mediated L. pneumophila restriction is caspase 1-dependent and signaling through this pathway results in the rapid death of infected cells [26], [27], [28]; a role consistent with its inclusion in the Nod-Like Receptor (NLR) superfamily of cytosolic pattern recognition sensors [29].
Proliferation and differentiation of transplanted cells appears to play a negligible role, consistent with the persistent functional and structural benefits of allogeneic CDC therapy long after the immunologically mismatched cells have been cleared (Malliaras et al, 2012).
Thus, although juvenile hormone maintains its traditional role as gonadotropin in B. terrestris, vg has already been co-opted into a novel role, consistent with the model that Bombus represents an intermediate stage in the evolution of eusociality.
Also, although additional rare CNVs overlapping exons may play a minor role, consistent with previous results (Bassett et al. 2008; Williams et al. 2013), methods for studying small CNVs require refining.
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Additionally, the observation that during temperature stress and bleaching, corals have increased fluorescence in their tissues [83] supports roles consistent with photoinduced FP activation [84] and antioxidant potential.
Over 150 imprinted genes have now been identified in placental mammals [ 26], a significant proportion having growth regulatory roles consistent with the parental conflict hypothesis [ 27, 28].
Furthermore, the novel targets we identified include genes that have roles consistent with Nodal activity, such as notum1a and smarcd3b, which have roles in head formation through Wnt antagonism [ 37] and establishment of left-right asymmetry [ 38], respectively.
If obstetric interventions played important roles, consistent with previous studies, we sought to examine whether such interventions bring benefit or harm to newborns, especially in terms of biological indicators at birth.
Our data indicate that, in addition to the IGF pathway, a second mammalian fetal growth regulatory axis exists in which oppositely imprinted genes have evolved roles consistent with the parental conflict hypothesis.
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