The undefined part of the aspirant's role gained definition and stabilized as it "filled up" with validated role components.
The role component thereby intersects with the scene component in organizing scriptlets that refer to these single activities.
When an aspirant was allocated a role component already performed by incumbents, those incumbents either relinquished that role component or shared responsibility for it with the aspirant.
These observations offer new insight into the function of stress granule components with roles in stress granule assembly and mRNP regulation.
Moreover, when added to cells in culture at moderate micromolar concentrations, celecoxib was shown to affect several additional cellular components with roles in cellular proliferation and survival (Grösch et al, 2006).
A specific role of TGF-β in CADASIL can be inferred from the fact that fibronectin, fibrillin-1 and members of the latent TGF-β binding protein (LTBP) family, important ECM components with a role in TGF-β bioactivation [ 35], were among the factors identified in the proteomic study on CADASIL brains [ 30].
This pool of data contributes to the view that the circadian system is comprised of multiple oscillatory components, with the role of the SCN being a master timer synchronizing these disparate cell populations (Stratmann and Schibler, 2006; Liu et al., 2007).
This system-level perspective on muscle control and aerodynamic mechanisms is thought to be a fundamental bridge in any attempt to link the function and performance of the various flight components with their particular role for wing motion and aerodynamic control in the behaving animal.
Accordingly, we will propose a new belief structure called Active Multi-layer Casuality Graph as shown in Figure 1, which seamlessly incorporate multiple components with different roles and levels, including Botnet, Evidence, Symptom and Actions, into the same active evidential reasoning framework.
The cell cycle variation in their abundance, their localization within the cell, and the sensitivity of their distribution to depletion of components with known roles in generating asymmetric spindle pulling forces, provide strong evidence that the invaginations are pulled by the same force-generating machinery that leads to asymmetric spindle positioning.
