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Peter Neufeld and Barry Scheck (Op-Ed, June 5) make an important point that is often missed in our focus on the role DNA has played in freeing innocent people from prison, including some from death row.
PD Smith The Music of Life: Biology Beyond Genes, by Denis Noble (Oxford, £7.99) Discovering the role DNA plays in creating proteins is one of the great achievements of 20th-century biology.
Beyond its quasi-digital-informational role, DNA possesses mechanical structural characteristics that dictate its response and action in response to deformations of the double helix that are inevitably involved in all aspects of DNA metabolism.
We are interested in probing the role DNA structures may have in attracting enzymes involved in DNA repair, recombination and chromatin modification, as some of these may be involved in expansion of the repeat or transcription repression mediated by the repeat.
To determine if the impact of DNA on biofilm formation was due to a structural role, DNA from R36A was broken by sonication for 5 min at 0.63 A and 50 60 Hz in a Transsonic T570 (Elma, Germany), and added to the medium at 1000 ng/ml.
Simultaneous methylation of several tumor suppressor genes indicates the important role DNA methylation is playing in breast cancer development.
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Folic acid plays a major role in DNA methylation and DNA synthesis.
DNA-dependent protein kinase (DNA-PK) has an important role in DNA double-strand break repair.
Recently, several large-scale studies reported the evolutionary roles of DNA methylation; however, the role of DNA methylation on brain evolution is largely unknown.
Portending a possible role for DNA beyond biology, a team of researchers at Bell Laboratories and Oxford University has fashioned molecular-sized motors out of the chemical that stores the genetic code.
We investigated the role of DNA sequence variation in modulating the observed changes in gene expression.
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