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Within and between regions of interest (ROI), group analyses were performed for both studies with statistical parametric mapping (SPM99).
Global or ROI group differences were assessed using a Mann-Whitney test, and correlations using Spearman's rank order correlation coefficient.
Although the aim of this study was to determine predictors of PIB-PET status for the individual, we also performed voxel-wise and specific ROI group analyses.
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End time was compared between stretched and unstretched ROI groups, for both total and directional edge intensity, using paired student's t-tests on the range RI [0.1, 0.9].
After defining our 4 ROIs (group peaks closest to those identified in Vigneau et al. 2006), eigenvectors (i.e., time series) were extracted from each subject's individual activation map thresholded at P < 0.05 uncorrected at the closest maxima within a distance of 8 mm of the group peak voxel.
Among these areas, there was no evidence that the total counts of Fos-positive neurons differed between the experimental and control groups (F < 1), nor was there a ROI by group interaction (F < 1; Figure 4).
In a first set of ROI analyses, group average ROIs were derived from significant tool or animal category-specific clusters within each age group's average activation map.
The 48 resulting covariance maps for each seed ROI (2 groups of 12 subjects, two sessions) were then tested for significant group × session interactions.
At present, luminescence signals are collected from images after identifying Regions of Interest (ROIs) — a group of pixels mapped to a luminescent region or grain; the sum of the net ROI signal provides the measure of luminescence for each grain.
In the following sections, regions of interest (ROIs) examined group differences (a) along the left ventral visual pathway including critical OT regions, (b) in left TP regions which were hypothesized to be dysfunctional in dyslexic readers, and (c) in left frontal language areas which were identified with dyslexic abnormalities in the whole-brain analyses.
Except for TroT and WT ROIs of group C (Table 3), we found that there was significant inter-group differences with the exception of TenT between groups A and B (p=0.222).
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