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Despite recent work in rodent tissue or cell lines, there is a paucity of literature concerned with the culture of human muscle derived cells (MDCs) in engineered constructs.
Precision-cut tissue slices, prepared from human or rodent tissue, provide a unique ex vivo model system that captures the complexity of organs, and they are widely used for ADME/Tox drug testing.
Comparative in vitro autoradiography on human and rodent tissue slices.
Grafts containing rodent tissue have proved useful for studying the cellular and biochemical features of neoplastic progression at different time intervals following in vivo exposure to carcinogens.
Moreover, the in vitro binding behaviour of [11C]Me@HAPTHI to human NET cell membranes as well as human and rodent tissue slices was examined.
Similar results were obtained in rodent tissue with other commercially available antibodies (data not shown).
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However, many researchers perform immunohistochemistry on tissues from experimental animals, particularly rodent tissues.
Butler, M., Stecker, K. & Bennett, C. F. Cellular distribution of phosphorothioate oligodeoxynucleotides in normal rodent tissues.
UV-DDB is also deficient in many rodent tissues, exposing a shortcoming in rodent models for cancer.
For lysosomes, definitive studies in this area have been restricted to rodent tissues due to technical constraints.
The objective if this study was to identify the IGF-1Ec forms or processing product(s), other than mature IGF-1, generated in different human and rodent tissues and particularly in human skeletal muscle after exercise-induced damage.
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