Sentence examples for rodent models including from inspiring English sources

Several types of stem cells have been used to treat ischemic brain injury in rodent models including neuronal stem cells, mesenchymal stem cells and hematopoietic stem cells.

Dr. Neumaier's research focuses on the study of complex emotional behaviors involving learning, motivation, and stress responses and he uses a variety of molecular, pharmacological, and behavioral strategies in rodent models including transgenic and intersectional viral vector strategies to manipulate and interrogate specific cell types in the brain.

These findings demonstrate that Tsc2-deficient adipocytes are insulin resistant and mimic some aspects of insulin resistant adipose tissue from rodent models, including down-regulation of IRS proteins and GLUT-4 and increased expression of GLUT-1.

Auraptene was effective in preventing the chemical carcinogenesis in various rodent models including skin [ 3], tongue [ 6], esophagus [ 7], liver [ 8, 9], and colon carcinogenesis [ 10- 13].

Various approaches are effective in rodent models, including treatment with an anti-C5 mAb [ 50], soluble complement receptor-1 and a DAF-Ig fusion protein [ 51, 52].

I3C has also been shown to protect against carcinogen-induced tumours in a range of rodent models including liver, tongue, skin, mammary tissue and colon [ 7- 12].

The primary differences in experimental design in rodent models include the (a) duration of hypoxia (15 to 150 min) to mimic mild versus moderate/severe neonatal HII and (b) the depth (30℃ 35℃), duration (3 26 hr), or time interval after HII (0 2 hr) when HT was initiated.

The rodent model includes exposure to diet, host microbiota and saliva as well as the mechanical hydrodynamic forces that are typically found in the mouth environment, which can dampen the antibacterial efficacy.

Indeed, AAV (adeno-associated virus -mediated gene therapy for inherited retinal disorders has been successful in a virus -mediatedal models, includingenedentherapyanine models oforeber congeninheritedretinalLCA) (15– 20), the CNGA3 andisorderseficiency mouse models (21, 22) and canine models of CNGB3 mutation/deficiency (23).

These robust cardiac differentiation methods have provided cells for cardiac drug testing in vitro4,11 and xenotransplantation of human PSC-derived cardiomyocytes (hPSC-CMs) in animal myocardial infarction (MI) models, including rodents, pigs, and nonhuman primates (NHPs 12,13,14.

A number of studies have demonstrated that CNTF is a potent neuroprotective factor for striatal MSNs in animal HD models, including rodents and primates.