We further investigated if the hairpins in T. gondii are actually expressed and checked sequence homology of the mature sequences in human and rodent examples from miRBase against the predicted hairpins.
For example, the rodent model created for the Pro250Arg FGFR1 mutation, which causes Pfeiffer syndrome, develops synostosis of the frontal, sagittal and coronal sutures [ 21] whereas in humans this mutation commonly affects only the coronal suture.
Such a study could overcome the limitations of the human FcεRI mouse as well as other rodent model organisms, for example, the rat, which although shares IgE receptor biology with humans and is therefore a valuable model in allergy research (174– 176), but again would have to get tumors either grafted or artificially induced.
For example, in a rodent model, hypoxia induced by angiogenesis inhibition resulted in stimulation of tumor cell invasion rather than inhibition, as anticipated [ 58].
Cells transformed by human adenoviruses (Ad) exhibit differential capacities to induce tumours in immunocompetent rodents; for example, Ad12-transformed rodent cells are oncogenic whereas Ad5-transformed cells are not.
A rodent, for example, cannot simultaneously suckle her young and forage for the food and water required to sustain lactation [18].
In the rodent, for example, at least two major atlases [36], [37] offer fine parcellations of the rat brain whose boundaries can be quite different over large regions [38], but which have not yet been systematically compared.
The observation that some projections are entirely Zn negative is borne out by studies in rodent, for example, projections from the cingulate, retrosplenial, perirhinal, and lateral entorhinal cortices to mouse visual cortex are Zn negative (Garrett et al. 1992).
This can be interpreted in terms of the stabilizing selection model with an intermediate phylogenetic mean: the proposal of a small ancestral rodent (for example) permits a tendency to evolve back toward the mean within the rodent clade, while the proposal of a large ancestral carnivore (for example) permits the same tendency in the opposite direction within the carnivore clade.
Work in rodents, for example, has utilized mazelike environments in which the animal is required to learn the location of a reward or an escape platform.
