Sentence examples for rod region from inspiring English sources

AO therapy is applicable to nearly all types of mutations occurring in this rod region and is predicted to be able to transform more than 60% DMD to near-normal phenotypes or milder Becker muscular dystrophies [18] [20].

The apoptosis, at least for the LMNA E82K or the mutations in the rod region of Lamin A/C, might be an important mechanism causing continuous loss of myocytes and lead to myocardial dysfunction.

Our results suggested that the apoptosis, at least for the LMNA E82K or the mutations in the rod region of Lamin A/C, might be an important mechanism causing continuous loss of myocytes and lead to myocardial dysfunction.

Additionally, the mAb 8D4 has been shown to not recognize the calpain-cleaved 47 kDa N-terminal fragment of Talin, as the mAb 8D4 epitope lies in the Talin rod region (residues 482 636) [27].

In contrast, no particular sequences in the rod region with net negative charge were identified as important for self-assembly, yet a minimal area from this region is necessary.

Its rod region consists of a series of helical bundles.

Relative to the extreme 90% distribution of japonica ROD regions falling in the 5% right tail of the genome-wide FST distribution, broader FST distribution of the soybean ROD regions is likely due to much longer LD distances (120 kb) of the wild soybeans relative to those of the wild rice and maize (<10 kb), as shown in our LD estimation described above.

A full understanding of how these properties vary along the length of the rod has implications for the engineering of these rods regions in exon skipping and minidystrophin therapies.

Taken together, all these data reveal that a common mitochondria-mediated signaling network underlies enhanced apoptosis in DMD iPSC-CMs (Fig. 4E), which could account for dilated cardiomyopathy in DMD patients with a Rod-region-specific dystrophin gene deletion.

Mutations in the middle and distal part of the slow/β-cardiac MyHC rod (LMM) region have been associated with several distinct morphological and clinical phenotypes depending on the location of the mutated residue.

The presence of CRX binding sites is a feature shared with other opsin regulatory regions: the mammalian LWS opsin LCR [ 40- 42], the mammalian rod expression region [ 94], zebrafish RH2 opsin LCR [ 95] and zebrafish SWS2 cis-acting regulatory elements [ 96].