Exact(7)
The paper will give an introduction to the basic ideas of Robustness Validation.
The emphasis is on prediction accuracy, with brief consideration of robustness, validation and computing burden.
For the three replicates, three different batches of iTLC sheets were used as part of the robustness validation.
To also ensure robustness, validation should be performed in a multi-center study [52], and selected cohorts have to represent the population targeted with the biomarker.
Robustness Validation is an approach to a failure-mechanism-driven qualification that was primarily initiated by the automotive industry but has a much wider range of applicability.
The robustness validation within CEN has led to a total test duration of 64 days in the final version of the TS-2 method while the TS-2 experiments during this study lasted 36 days.
Similar(53)
In this paper, we present the development, robustness and validation of the modelling process together with the predicted results for the OBR system.
Various sources of uncertainty such as prediction uncertainty, uncertainty of prior information, and observation errors are included within the optimization process in order to improve the robustness of validation experiment design.
The models have been validated for their stability and robustness using group validation and bootstrapping techniques and for their predictive abilities using an external test set of nine compounds.
The CoMFA and CoMSIA models have been further validated for their stability and robustness using group validation and bootstrapping techniques and for their predictive abilities using an external test set of ten compounds.
Much research has been done on various aspects of QSAR modeling, such as validation, robustness, and domain applicability of models [14].
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