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(iii) Finally, to extract the robust genes, we identified the robustness score that is the maximum in the sorted VC list.

In order to support the validity of this AD robustness score, it is worth analysing the contribution of simpler measures (or concepts) that are incorporated in the newly proposed score.

Moreover in the relapse versus remitting network, two of these genes, miR-18b and miR-599 appear to be correlated with a direct probabilistic relationship (with a 733 robustness score).

Figure 2 illustrates the robustness score mechanism.

† Robustness Score: Sum over Resource responses 1 6.

The robustness score in the VC list first increases as it moves down, and then at a certain point achieves a maximum robustness score and thereafter starts decreasing.

From this network we chose the miRNA with the higher degree (hsa-miR-96), the two with arcs showing the highest robustness values (hsa-miR184 with 1557 robustness scores and hsa-miR-193a with 1358 robustness scores) and the other parent of hsa-miR96, the hsa-miR-148a.

Genes mapped to the trait of mechanical OIH were ranked after subjecting the data to the robustness scoring procedure described in Methods.

The ratio of the value for a system with modified coupling to that of the WT yields a measure of relative robustness: a score greater than 1 implies a clock that is more robust than the WT; a score less than 1 a less robust network (see Additional file 1, section 4 for details).

One may test the robustness of a score model by examining how well the score model fits the database search score histograms.

Finally, the strong association between the recommendation scores and GPs' own vaccination behavior scores confirms the robustness of the global score as a proxy for VH.