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Robustness of screening tools is variable, in terms of reliability, validity and prediction of injury risk.
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Its repeat identification in the Natural Product screen attests to the robustness of the screening protocol.
Functional studies on Itga11 and Chst5 demonstrated the robustness of this screening.
The results were analyzed to determine the two extremes of activity range and robustness of the screening assay.
To demonstrate the robustness of the screening method, we have re-transformed the rescued plasmids into wild-type yeast (data not shown) and salt hypersensitive mutant shs-2.
Besides the two mutants with attenuated P/R ratios, two acetate-requiring mutants were identified confirming the robustness of the screening procedure.
Overall, the homogenous cell growth and viability assay as well as the quantification by laser scanning cytometry yielded equivalent results which underlined the robustness of the screening platform in MSCs.
These results suggest the robustness of the screen.
However, concerns about the robustness of such screens require that the targets identified are validated independently.
The robustness of this screen was illustrated by the detection of essentially all of the known antifungal agents within the chemical library.
The similar results obtained for individual miRNA seed family members underscore the importance of this region in target selection and prove the robustness of our screen.
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CEO of Professional Science Editing for Scientists @ prosciediting.com