A criterion which incorporates experimenters' prior beliefs about the importance of each effect is introduced to compare orthogonal, or nearly orthogonal, main effects designs with robustness to interactions as a secondary consideration.
Biological evolution has found ways to build organisms with astonishing complexity, where both, the number of elements and the robustness of interactions between them, often exceed those of engineered products.
Weighted analysis to test the robustness of interactions was conducted using R (version 2; R Foundation for Statistical Computing, Vienna, Austria).
Reactions R34 (pyruvate dehydrogenase/citrate synthase), R36 (isocitrate dehydrogenase) and R41 (malate dehydrogenase) are steps in the TCA cycle regulated by ATP, which could explain the robustness of interactions between reaction pairs [R34, R36] and [R34, R41] [ 23, 25, 26].
For determination of independent predictors for hospital mortality, odds ratio was estimated on the basis of multivariate logistic regression analysis, including exploration for robustness and interactions using likelihood ratio tests.
The audience is there, so is the content, but the robustness of interaction needed to keep that story going is arguably missing.
Radical criticisms that dispute the robustness of interaction between motor and semantic processes in language comprehension are scarce [21].
It has been proposed that the robustness of interaction networks to anthropogenic disturbances increases with their level of nestedness, since the loss of extinction-prone specialists is less likely to trigger the extinction of other specialists in nested networks [7], [13].
To assess the robustness of interaction models, we used two different strategies: an internal validation procedure based on bootstrap re-sampling methods [ 52] and a correction for multiple testing using the FDR principle [ 53].
The DPM-PAA system outperformed all other ASDs in various stability conditions (dry-state, in the presence of moisture and in solution state), which was attributed to the drug's low crystallization tendency, the strong DPM-PAA interaction, the robustness of this interaction against moisture or water and the ability of PAA in maintaining DPM supersaturation.
