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The implemented system clearly demonstrates the provided robustness advantage through the NCC infrastructure.
Additionally, SigB was suitable to predict the robustness advantage towards both lethal acid and oxidative stress originating from preexposure to mild acid stress.
In addition to protein SigB and catalase activity, clpC and clpP were also suitable to predict the robustness advantage towards multiple lethal stresses, namely lethal acid and oxidative stress, following mild acid stress pretreatment.
Mild heat stress pretreatment provided a robustness advantage towards lethal heat stress treatment, and also conferred cross-protection towards lethal acid stress, whereas no increased resistance towards lethal oxidative stress was observed upon mild heat stress pretreatment (Figure 2b).
Both unstressed and mild stress treated cells were also exposed to lethal stress conditions (severe heat, acid and oxidative stress) to quantify the robustness advantage provided by mild stress pretreatment.
SigB was also significantly correlated to lethal heat stress robustness upon mild acid stress pretreatment, but because mild acid stress pretreatment did not significantly induce a robustness advantage towards lethal heat stress (Figure 3), SigB was not identified as a long-term biomarker for this condition.
Similar(54)
The combined approach of the AWF has computational and performance robustness advantages [4].
Some methods provide an accurate estimate in some situations, while others may have complexity or robustness advantages.
MI seems to have some robustness advantages over mixed models, and therefore we would recommend it as a method of choice.
This supports the notion that robustness confers advantage for evolvability.
With respect to energy consumption, node lifetime, and network robustness, several advantages are associated to a self-regulating network planning.
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