In addition, pathways occupied by robustly-associated genes can highlight additional genes with more modest effects on susceptibility but which may provide better targets for biomarker and drug development (Penrod et al. 2011).
The inclusion of patient experience as one of the pillars of quality is partly justified on the grounds that patient experience data, robustly collected and analysed, may help highlight strengths and weaknesses in effectiveness and safety and that focusing on improving patient experience will increase the likelihood of improvements in the other two domains.
The report from Newton-Cheh et al. [ 24] highlights the effort required to robustly explore just a single susceptibility locus for hypertension.
Here, we will highlight three ambitious novel therapeutic approaches for this condition, each robustly driven by primary neuroscience.
This review highlights the urgent need for further research to more robustly quantify, and address, what appears to be a considerable burden of foot disease present in general inpatient populations.
The leech example highlights a critical aspect of co-option: it is most robustly studied within a phylogenetic framework because it is inherently historical.
Mary robustly asserts that there were many critics of the UN Panel's conclusion, highlighting Ian Plimer's Heaven and Earth: Global Warming - The Missing Science; to the contrary, see Mark Hertsgaard's Hot: Living Through the Next 50 Years on Earth.
And Haley Reinhart, who always appeared on the show as if she were about to be scolded — and in fairness, she often was — was one of the highlights here, comfortable on stage even in her dancing, and singing robustly.
Indeed, RAW264.7 cells showed robustly detectable enzymatic activity, which was strongly reduced in the Smpdl3b knockdown cells, highlighting SMPDL3B as an important phosphodiesterase enzyme significantly contributing to substrate hydrolysis on macrophages.
Trudeau said Thursday he "highlighted to the secretary general that part of Canada wishing to re-engage robustly with the United Nations and in multilateral engagement around the world includes looking towards a bid for the UN security council" as vacancies open up.
