Sentence examples for robustly extend from inspiring English sources

In contrast to previous reports, we find that DR can robustly extend the lifespan of worms lacking the AMP-activated protein kinase catalytic subunit AAK2 or the histone deacetylase SIR-2.1, highlighting the importance of first optimizing DR to identify universal regulators of DR mediated longevity.

We were unable to detect a significant replicative lifespan extension from buffering the culture medium under any of the conditions examined, including those conditions that robustly extend chronological lifespan.

Metformin and Phenformin Robustly Extend Lifespan, Related to Figure 1 Table S2.

However, BDR robustly extended the lifespan of the double homozygous sir-2.1 ok434) sir-2.1 ok434k444) X mutants (FIVure sir-2.3 ok444 sir-2.3 ok444.

Since BDR therefore reduces reproduction and feeding rates while robustly extending lifespan, it is a method of dietary restriction that successfully recapitulates many aspects of mammalian DR (Table 1).

Unlike previously published results, mutations in either aak-2 or sir-2.1 fail to block lifespan extension by DR using our protocol, which robustly extends lifespan of wild type worms whilst reducing both food intake and reproduction.

Drug pretreatment of E. coli robustly extended worm lifespan (+33%, p < 0.001; Figure 2C; Table S2).

Rapamycin, an inhibitor of the mechanistic target of rapamycin (mTOR), robustly extends the lifespan of model organisms including mice.

Here, we investigated requirements for stress defense and NAD+-associated mechanisms, using a new liquid feeding DR method that robustly extends lifespan and minimizes maintenance.

Yeast restriction in the fly robustly extends lifespan of both male and female flies, as do mutations of the insulin receptor (InR) and of the InR substrate homolog encoded by chico (Clancy et al., 2001; Tatar et al., 2001; Tu et al., 2002).

Our findings robustly confirm and extend the previous reports of these phenomena.