Sentence examples for robustly conserved from inspiring English sources

We show that the modular organization of chromosomes is robustly conserved in syntenic regions and that this is compatible with conservation of the binding landscape of the insulator protein CTCF.

Despite these differences, the intrinsic structural features of the signal recognition particle are so robustly conserved throughout evolution that ribonucleic particles reconstituted in vitro by mixing bacterial, archaeal, and, eukaryotic components are functional.

Moreover, M6a mRNA was also downregulated in the hippocampal formation of psychosocially stressed tree shrews [11] indicating that the effect of stress on M6a expression is robustly conserved across species and is reproducible with different stress paradigms.

The evidence that supports the first interpretation is: a) the trans eQTLs were identified by the same methods that found the cis eQTLs, which are robustly conserved; and b) our genome wide p-values are based upon permutation analysis which takes into account the data structure, and thus these are likely to be good estimates.

Thus, profiles are robustly conserved across technical replicates of both test and reference DNA.

We compared this to the TAAR5 clade which also is robustly conserved without pseudogenization.

The most robustly age-downregulated gene conserved in all three species is CAMK4, a key component of the cAMP signaling cascade that links synaptic activity to CREB-dependent transcription and modulates synaptic plasticity [14], [22].

The most robustly age-upregulated of these conserved genes is apolipoprotein D, which has been shown to protect against oxidative stress and extend lifespan in Drosophila [18], [19].

First, comparisons across different metabolic states can identify conserved modules comprising robustly interacting reactions that may be co-regulated by a common allosteric effector.

Where known, trypanosome Rab functions are broadly conserved when orthologous relationships may be robustly established, but specific functions for RabX1, X2 and X3 have yet to be determined.

As shown in other organisms, conserved miRNAs tend to be more robustly expressed than species-specific miRNAs [ 39- 41].