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But I remain cautious and talk about a lack of robust trials and meta-analysis.
Ben Goldacre has been championing this government's efforts to push evidence-based policy, based on the data generated from well-designed robust trials (the effort should be applauded but the temptation to use only evidence which supports the Ministers' views still seems too tempting for them to refuse).
Thus, more robust trials are needed to build evidence about these interventions.
It is costly compared to first generation antipsychotics (FGAs) LAIs and there are no robust trials comparing AM with FGAs.
Though of course the power of the placebo effect working its psychological magic cannot be ruled out — not until they've clinically tested their stuff against it in robust trials.
Community Health Workers (CHWs) have been recommended to reduce diabetes disparities, but few robust trials of this approach have been conducted.
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We need a robust trial of all the options available before we know its true place".
This lack of an independent, external party and a defined audit trail reduces the process validity, leaving it exposed to tampering, resulting in a less robust trial design.
The study enrolls 4000 adults (ages 18 75) from both primary and specialty care practices who have not had either a prior inadequate response or clear-cut intolerance to a robust trial of protocol treatments during the current major depressive episode.
The use of multiple operators to measure repeatability provided a more robust trial compared to previous studies that involved only single operators [28], [29], [30].
Nevertheless, with greater resources, a more robust trial design could have been adopted.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com