Exact(22)
Despite the intrinsic dynamic, interdependent and nonlinear relationships of their parts, complex biological systems exhibit robust systemic stability.
Both local mucosal immunity and robust systemic responses can be achieved through mucosal vaccination.
Ocular immunization of guinea pigs with either strain induces robust systemic and mucosal immune responses that protect against homologous challenge with wild-type Shigella.
"We should be looking at a temporary levy in the short term to ensure dairy farmers don't walk off the land and that should be part of a robust systemic independent look at the dairy sector because clearly it appears to be verging on market failure given what has occurred".
vaccination of MERS-CoV RBD-Fc induced systemic humoral immune responses comparable to those induced by s.c. vaccination, including neutralizing antibodies, but more robust systemic cellular immune responses and significantly higher local mucosal immune responses in mouse lungs.
Despite eliciting a robust systemic envelope (Env -specific IgG rEnv -specificell as durable mIgG IgA responses, the masernal vaccine did not have a discernible impact on infant oral SHIV acquisition.
Similar(38)
These results demonstrate efficient SL vaccine delivery utilizing a combination of a muco-adhesive and surface neutral liposomes to achieve a robust mucosal and systemic immune response.
By encouraging the public to view groups like Black Lives Matter (which has offered a robust critique of systemic police violence against African-Americans and has organized peaceful direct actions but has no links to terrorism or violence) as a threat, the designation indirectly emboldens private violence against black activists.
Additionally, robust, antigen-specific systemic antibody (serum IgG1 and IgG2a) and CD8+ CTL responses were also generated.
Given that TSS is characterized by a robust elevation in systemic levels of several cytokines and chemokines, neutralization of key cytokines and/or chemokines could have therapeutic potential, as in other inflammatory diseases [14], [15].
However, circulating acute-phase proteins (for example, CRP) remain robust indices of systemic pro-inflammatory status.
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