Sentence examples for robust reactivation from inspiring English sources

Combined treatment of DZNep, an inhibitor of histone methylation [23], with HDAC inhibitor TSA causes a robust reactivation of CDKN1C expression.

Treatment of the GFP reporter cells with the LLO peptide resulted in robust reactivation of the GFP reporter (data not shown).

Initially, we tested increasing concentrations of 5-aza-2′-dC in combination with Dnmt1 knockdown to determine a 5-aza-2′-dC concentration for which the depletion of Dnmt1 by siRNAs yielded robust reporter reactivation, but where 5-aza-2′-dC treatment alone does not elicit reactivation.

A second double-mutant in which a Q at position 146 was combined with an E at position 363 was also found to exhibit robust enzyme reactivation following cyclosarin exposure, with an rate increase of >21,000-fold relative to wt hCE1 (Table 1).

Another roadblock to cellular reprogramming is the requisite early reactivation of a robust transcriptional circuitry governed by OCT4 and SOX2 (Buganim et al., 2012).

To identify regions with reactivation or suppression effects that were robust across both probe modality conditions, we performed 2 three-way conjunction analyses, one for reactivation: [Aud Aud > NOVEL Aud] ∩ [Aud:Vis > NOVEL Aud] ∩ [Modality:Aud > Modality:Vis] and one for suppression: [NOVEL Aud > Aud Aud] ∩ [NOVEL Aud > Aud:Vis] ∩ [Modality:Aud > Modality:Vis].

The subpopulation of cells with high mER levels exhibited early and more robust activation, peaking at 10 min with a reactivation at 60 min, whereas the subpopulation of cells with low mER levels were only capable of weakly activating ERKs at one early time point (6 min).

Thus, forced nrg1 reactivation in the absence of cardiac injury induces robust myocardial hyperplasia in adult zebrafish, adding many new layers of myocardium over weeks of continued cardiomyocyte proliferation.

This implies that higher levels of mER-α associated with more robust early ERK activation are also responsible for the sustained ERK reactivation at the later stage.

The current study extends these findings by showing that the same relation can be demonstrated by using a different measure focusing more specifically on the reactivation of ruminative thinking and that the relation remains robust even when neuroticism is measured several years before the assessment of rumination and depressive symptoms.

The chloroquinone expt (thought to be via KAP1) has only a minor effect on HCMV reactivation and you need subsequent NF-kB stimulation to make it more robust.