But, even by those standards, a speech on Tuesday by William Hague, the British foreign secretary, to an audience in Berlin seemed designed to set yet more robust markers against the very idea of national governments relinquishing powers to a central European authority.
These parameters were robust markers of vagal activity.
Tissue-specific DNA methylation patterns have been previously investigated for their applicability in the identification of forensically relevant body fluids, however there is still a lack in robust markers.
We thus concluded that our AFLP methodology gave highly robust markers.
Accordingly, a genetic analysis of F. tularensis isolates including Ft-M3 and Ft-M6 should be complemented with analysis of more robust markers, such as SNPs and/or INDELs to ensure correct phylogenetic classification.
Recently, our group and others demonstrated that lineage-restricted transcription factors such as OCT4 and NANOG are robust markers for the diagnosis of germ cell tumors, including those in the central nervous system[26] [29].
However, because of the inherent phylogenetic limitations of these tools, final strain assignment to specific strain lineages should be based on more robust markers such as SNPs or LSPs.
Molecular data, especially DNA sequences, provide robust markers for mycological novelties even when the material for study is limited, such as in the case of the tiny basidiomata of Hymenogaster.
We confirmed that robust markers of phagosomal maturation like Rab7, LAMP1 and LAMP-3 were excluded from mycobacterial phagosomes in DHA-treated cells, showing reduced fusion of Mtb-containing phagosomes with late endosomal compartments.
Taken together, our findings suggest strain lineages in MTBC should be defined based on phylogenetically robust markers such as single nucleotide polymorphisms or large sequence polymorphisms, and that for epidemiological purposes, MIRU-VNTR loci should be used in a lineage-dependent manner.
This characteristic represents a satisfactory bound on the error of the solution for a given mixture, and can be thought of as the result of a basis matrix that contains genes that together form a complete but parsimonious set of robust markers for the cell types of interest.
