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The surprisingly robust function of the S217A mutant may indicate that multiple myosin-Va molecules cooperate to ensure that melanosomes remain attached to actin tracks during transport.
Hence, the dimer promotes the robust function of bistable switches by preventing the uninduced (induced) state from randomly being induced (uninduced).
Based on our results, we conclude that mir-34 and mir-83 function together to help create or maintain robust function of the genetic network controlling gonad morphogenesis, such that the development of this important organ is protected from the temperature changes C. elegans may encounter, either the rapid oscillations tested here or subtler changes experienced in the wild.
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With respect to this platform, we discuss the essential role of learning for robust functioning of the robot and sketch the concept of an integrated architecture for situated learning on the system level.
In a practical system, the interleaving delay budget is constrained not only by the overall delay budget but also by the delay budget necessary for the robust functioning of the source coding and the channel coding.
The functional demands on the DAT1 regulation are seemingly contradictory since the vital necessity of assuring the robust functioning of the dopaminergic system coincides with the need for plasticity and rapid fluctuations in the transcription rate.
Feedback control mechanisms are vital to the robust functioning of gene regulatory and metabolic pathways.
Accordingly, robust functions of α-MSH have been defined in the molecular processes of skin pigmentation, apoptosis, inflammation, and UV-induced immune suppression.
To guarantee that we had selected a robust function set of genes for drugs and diseases, we included other functionally related genes, thereby extending our understanding for drug mode of action or disease pathophysiology.
Our analysis of the model provides an understanding of the system requirements for robust function by uncovering the role of specific reactions operating in a physiologically plausible range of parameters.
The proposed morphing method is applied to a truss core panel and a human head model, clarifying the robust function and high efficiency of the method proposed in this study to deal with complex 3D product model sustainable optimization.
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